Relationship of treatment for hypertension and stroke mortality.

ing," but would emphasize that those were trials of isovolemic hemodilution. Hypervolemic hemodilution offers greater opportunity to improve cerebral perfusion because of its positive effect on cardiac function. Isovolemic and hypervolemic hemodilution are two different methods aimed at augmenting reperfusion. Isovolemic hemodilution probably does not improve outcome. We feel that our study of hypervolemic hemodilution provides enough encouragement to conclude that further study of this technique is definitely needed. James C. Grotta, MD The University of Texas Health Science Center at Houston Houston, Texas